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Zoloft

Sertraline Hydrochloride
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Sertraline Hydrochloride is the active ingredient anchor for this record. Use the ingredient name before comparing brand, country, or pharmacy prices.

active moietySertraline Hydrochloride
administration routeOral
price comparison status2 snapshots
safety signal rating46 / 100
SSRI antidepressantgeneric anchorpinned-popular-watchlist
price index

Price Comparison

$6.04USvsCA$9.91CA

Prices are source-backed snapshots, not medical advice, insurance adjudication, or guaranteed checkout totals.

query trend --id 30 --12m

Price Trend Index

Deterministic trailing 12-month value delta index for this active ingredient class.

Rising Fast3M: +1.5%12M: +6%
Jul 2025
▂▃▃▅▅▅▆▇██
Jun 2026
Jan 2026$5.89
Feb 2026$5.89
Mar 2026$5.93
Apr 2026$5.97
May 2026$6.02
Jun 2026$6.02
01 / chemistryMaker not enriched yet

Ingredient Breakdown

active moietySertraline Hydrochloride
formulationOral SSRI antidepressant
mechanism of action

SSRI antidepressant

available strengths
Strength varies by package/NDC; inspect source label before comparing prices.

label source: registry ↗

02 / ingredientsexcipients

Excipients / Maker Notes

  • Not enriched yet from label source.

Manufacturer Notes

  • This record is normalized from the openFDA NDC seed. Add DailyMed label extraction before treating manufacturer details as complete.
03 / safetyclinical signals

Steps To Take Safely

  1. Confirm ingredient, dose, timing, food instructions, and interaction warnings with a clinician or pharmacist.
  2. Use the same ingredient name when comparing brand, generic, country, and pharmacy options.
  3. Do not split, crush, stop, or substitute extended-release products unless the label or clinician says so.
  4. Watch for severe allergic reactions, bleeding, mood changes, breathing issues, or other label-specific red flags.

Side-Effect Signals

  • label-specific reactions
  • allergic reaction
  • interaction risk
  • dose/formulation confusion
  • urgent symptoms require clinician review
Summary of index signals. Not active medical advice. Consult official labels and clinicians.

$ cat faq_guide.md

Frequently Asked Questions

> What active ingredient is in Zoloft?

Zoloft is a brand-name prescription drug formulated with the active chemical substance Sertraline Hydrochloride. It belongs to the class hint group SSRI antidepressant and is designed for Oral administration.

> How does the US price for Zoloft compare to Canada?

Reference price notes index Zoloft with a US cash/retail cost of approximately $6.04 (recorded via Cost Plus Drugs) and a Canadian provincial formulary cost of $9.91 (recorded via Ontario Drug Benefit (ODB) Formulary). Comparative gaps fluctuate depending on packaging quantity, pharmacy checkouts, and local benefit tables.

> Can I buy a generic alternative for Zoloft?

Yes, Sertraline Hydrochloride represents the active molecule identifier. While generics utilize the same active ingredient, clinicians and pharmacists must verify specific bioequivalence boundary configurations before initiating substitution.

$ grep ingredient --same

Same Ingredient Sibling Records

All matches
Sertraline HclSertraline HclZoloft , Zoloft (Sertraline Hydrochloride) , ConcentrateZoloft , Zoloft (Sertraline Hydrochloride) , Concentrate